Directions to Self Regional Medical Center from Charlotte via I-77 / Chester.
This route is about 125 miles from downtown Charlotte.

• Head south from Charlotte on I-77 to Chester.
• Approximately 36 miles from Charlotte, take Exit #65 / Hwy 9 – Chester.
• Turn right after exit and drive about nine miles to Chester.
• At the first red light, turn left in order to stay on Hwy 9 (where a sign points to Whitmire).
• After about two miles, turn left at red light on to Highway 72 South. (A BP Station is on the right across intersection).
• Drive toward Whitmire.
• You’ll pass through Carlisle after about 15 miles. (Carlisle is midway between Charlotte and Greenwood).
• Stay on Highway 72 headed to Whitmire.
• When the road becomes four lanes, keep in the right lane.
• In Whitmire the four lanes split; take the right fork to stay on Highway 72.
• At the stop sign, turn right to stay on Highway 72 and head toward Clinton (which is about 18 miles).
• You will cross over I-26 just before you get to Clinton.
• After I-26, take turn left at the first red light on to Highway 72/56 truck route. (Don’t go straight, which is 72 business.)
• Follow the 72/56 truck route around Clinton.
• Go past the intersection where 56 splits off from 72
• Turn left at the next intersection to stay on 72 West; a sign will point left to Greenwood.
• Highway 72 will pass through the villages of Mountville and Clarks Hill and then pass over Lake Greenwood.
• As you enter Greenwood, you’ll pass several manufacturing plants and the Civic Center (on the left).
• After two minor red lights, you will turn left at the next red light in order to stay on Highway 221.
• You will go through two red lights and then turn right at the third light on to Marshall Road.
• Stay on Marshall Road as it crosses South Main Street.
• The hospital is two blocks on the right. Taking a right the next light will lead to the visitor parking lot.